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1

An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy

Thiele, Nikki A., Brown, Victoria, Kelly, James M., Amor-Coarasa, Alejandro, Jermilova, Una, MacMillan, Samantha N., Nikolopoulou, Anastasia, Ponnala, Shashikanth, Ramogida, Caterina F., Robertson, An

Journal:

Angewandte Chemie

Year:

2017

Language:

english

File:

PDF, 1.33 MB

english, 2017

2

Preclinical Evaluation of a High-Affinity Sarcophagine-Containing PSMA Ligand for 64 Cu/ 67 Cu-Based Theranostics in Prostate Cancer

Kelly, James M., Ponnala, Shashikanth, Amor-Coarasa, Alejandro, Zia, Nicholas A., Nikolopoulou, Anastasia, Williams, Clarence, Schlyer, David J., DiMagno, Stephen G., Donnelly, Paul S., Babich, John W

Journal:

Molecular Pharmaceutics

Year:

2020

File:

PDF, 510 KB

2020

3

[IEEE 2013 29th Southern Biomedical Engineering Conference (SBEC 2013) - Miami, FL (2013.5.3-2013.5.5)] 2013 29th Southern Biomedical Engineering Conference - 99mTc-MAA vs. 68Ga-MAA as Perfusion Agents

Amor-Coarasa, Alejandro, Milera, A., Carvajal, D. A., McGoron, A. J.

Year:

2013

Language:

english

File:

PDF, 296 KB

english, 2013

4

Spectroscopic, radiochemical, and theoretical studies of the Ga 3+ - N -2-hydroxyethyl piperazine- N ′-2-ethanesulfonic acid (HEPES buffer) system: evidence for the formation of Ga 3+ - HEPES complexes in 68 Ga labeling reactions

Martins, André F., Prata, M. I. M., Rodrigues, S. P. J., Geraldes, Carlos F. G. C., Riss, P. J., Amor-Coarasa, A., Burchardt, C., Kroll, C., Roesch, F.

Journal:

Contrast Media & Molecular Imaging

Year:

2013

Language:

english

File:

PDF, 400 KB

english, 2013

5

Synthesis of [11C]palmitic acid for PET imaging using a single molecular sieve 13X cartridge for reagent trapping, radiolabeling and selective purification

Amor-Coarasa, Alejandro, Kelly, James M., Babich, John W.

Journal:

Nuclear Medicine and Biology

Year:

2015

Language:

english

File:

PDF, 330 KB

english, 2015

6

-NOTA-CHSg and -CHSg Labeled Microspheres for Lung Perfusion and Liver Radiomicrospheres Therapy Planning

Amor-Coarasa, Alejandro, Milera, Andrew, Carvajal, Denny, Gulec, Seza, Leichner, Jared, McGoron, Anthony J.

Journal:

International Journal of Molecular Imaging

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

7

Lyophilized Kit for the Preparation of the PET Perfusion Agent [ 68 Ga]-MAA

Amor-Coarasa, Alejandro, Milera, Andrew, Carvajal, Denny, Gulec, Seza, McGoron, Anthony J.

Journal:

International Journal of Molecular Imaging

Year:

2014

Language:

english

File:

PDF, 1.34 MB

english, 2014

8

Comprehensive Quality Control of the ITG Ge-68/Ga-68 Generator and Synthesis of Ga-68-DOTATOC and Ga-68-PSMA-HBED-CC for Clinical Imaging

Amor-Coarasa, A., Schoendorf, M., Meckel, M., Vallabhajosula, S., Babich, J.

Journal:

Journal of Nuclear Medicine

Year:

2016

Language:

english

File:

PDF, 997 KB

english, 2016

9

Synthesis and pre-clinical evaluation of a new class of high-affinity18F-labeled PSMA ligands for detection of prostate cancer by PET imaging

Kelly, James, Amor-Coarasa, Alejandro, Nikolopoulou, Anastasia, Kim, Dohyun, Williams, Clarence, Ponnala, Shashikanth, Babich, John W.

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2017

Language:

english

File:

PDF, 3.42 MB

english, 2017

10

Radioiodinated Capsids Facilitate In Vivo Non-Invasive Tracking of Adeno-Associated Gene Transfer Vectors

Kothari, P., De, B. P., He, B., Chen, A., Chiuchiolo, M. J., Kim, D., Nikolopoulou, A., Amor-Coarasa, A., Dyke, J. P., Voss, H. U., Kaminsky, S. M., Foley, C. P., Vallabhajosula, S., Hu, B., DiMagno,

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 983 KB

english, 2017

11

Double Targeting Ligands with Modulated Pharmacokinetics for Endoradiotherapy of Prostate Cancer

Kelly, James M., Amor-Coarasa, Alejandro, Nikolopoulou, Anastasia, Wüstemann, Till, Barelli, Peter, Kim, Dohyun, Williams, Clarence, Zheng, Xiwei, Bi, Cong, Hu, Bao, Warren, J. David, Hage, David S.,

Journal:

Journal of Nuclear Medicine

Year:

2017

Language:

english

File:

PDF, 1003 KB

english, 2017

12

Continuation of Comprehensive Quality Control of the itG 68 Ge/ 68 Ga Generator and Production of 68 Ga-DOTATOC and 68 Ga-PSMA-HBED-CC for Clinical Research Studies

Amor-Coarasa, Alejandro, Kelly, James M., Gruca, Monika, Nikolopoulou, Anastasia, Vallabhajosula, Shankar, Babich, John W.

Journal:

Nuclear Medicine and Biology

Year:

2017

Language:

english

File:

PDF, 474 KB

english, 2017

13

An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy

Thiele, Nikki A., Brown, Victoria, Kelly, James M., Amor-Coarasa, Alejandro, Jermilova, Una, MacMillan, Samantha N., Nikolopoulou, Anastasia, Ponnala, Shashikanth, Ramogida, Caterina F., Robertson, An

Journal:

Angewandte Chemie International Edition

Year:

2017

Language:

english

File:

PDF, 1.33 MB

english, 2017

14

[ 18 F ]RPS-544: A PET tracer for imaging the chemokine receptor CXCR4

Amor-Coarasa, Alejandro, Kelly, James, Ponnala, Shashikanth, Vedvyas, Yogindra, Nikolopoulou, Anastasia, Williams, Clarence, Jin, Moonsoo M., David Warren, J., Babich, John W.

Journal:

Nuclear Medicine and Biology

Year:

2018

Language:

english

File:

PDF, 1.33 MB

english, 2018

15

Trifunctional PSMA-targeting constructs for prostate cancer with unprecedented localization to LNCaP tumors

Kelly, James, Amor-Coarasa, Alejandro, Ponnala, Shashikanth, Nikolopoulou, Anastasia, Williams, Clarence, Schlyer, David, Zhao, Yize, Kim, Dohyun, Babich, John W.

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2018

Language:

english

File:

PDF, 883 KB

english, 2018

16

90 Y-DOTA-CHS Microspheres for Live Radiomicrosphere Therapy: Preliminary In Vivo Lung Radiochemical Stability Studies

Amor-Coarasa, Alejandro, Milera, Andrew, Carvajal, Denny, Gulec, Seza, McGoron, Anthony J.

Journal:

Journal of Radiotherapy

Year:

2014

Language:

english

File:

PDF, 1.94 MB

english, 2014

17

Impact of elution impurities on DOTA and NOTA labeling with two commercial 68Ge/68Ga generators

Amor-Coarasa, Alejandro, Gruca, Monika, Hurez, Sophie, Gulec, Seza A., McGoron, Anthony, Babich, John W.

Journal:

Journal of Radioanalytical and Nuclear Chemistry

Year:

2018

Language:

english

File:

PDF, 847 KB

english, 2018

18

4-N-Alkanoyl and 4-N-alkyl gemcitabine analogues with NOTA chelators for 68-gallium labelling

Pulido, Jesse, de Cabrera, Maria, Sobczak, Adam J., Amor-Coarasa, Alejandro, McGoron, Anthony J., Wnuk, Stanislaw F.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.36 MB

english, 2018

19

A Single Dose of 225 Ac-RPS-074 Induces a Complete Tumor Response in a LNCaP Xenograft Model

Kelly, James M., Amor-Coarasa, Alejandro, Ponnala, Shashikanth, Nikolopoulou, Anastasia, Williams, Clarence, Thiele, Nikki A., Schlyer, David, Wilson, Justin J., DiMagno, Stephen G., Babich, John W.

Journal:

Journal of Nuclear Medicine

Year:

2018

Language:

english

File:

PDF, 1.59 MB

english, 2018

20

66Ga: A Novelty or a Valuable Preclinical Screening Tool for the Design of Targeted Radiopharmaceuticals?

Amor-Coarasa, Alejandro, Kelly, James, Ponnala, Shashikanth, Nikolopoulou, Anastasia, Williams, Clarence, Babich, John

Journal:

Year:

2018

Language:

english

File:

PDF, 1.63 MB

english, 2018

21

Albumin-Binding PSMA Ligands: Implications for Expanding the Therapeutic Window

Kelly, James M., Amor-Coarasa, Alejandro, Ponnala, Shashikanth, Nikolopoulou, Anastasia, Williams, Clarence, DiMagno, Stephen G., Babich, John

Journal:

Journal of Nuclear Medicine

Year:

2018

Language:

english

File:

PDF, 2.07 MB

english, 2018

22

[18F]Fluoroethyltriazolyl Monocyclam Derivatives as Imaging Probes for the Chemokine Receptor CXCR4

Amor-Coarasa, Alejandro, Kelly, James M., Singh, Pradeep K., Ponnala, Shashikanth, Nikolopoulou, Anastasia, Williams, Clarence, Vedvyas, Yogindra, Jin, Moonsoo M., Warren, J. David, Babich, John W.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.87 MB

english, 2019

23

Production, purification and use of 66Ga for “in vivo” screening of therapeutic compounds

Amor-Coarasa, A., Kelly, J., Ponnala, S., Nikolopoulou, A., Williams, C., Babich, J.

Journal:

Nuclear Medicine and Biology

Year:

2019

Language:

english

File:

PDF, 50 KB

english, 2019

24

Effect of the radiometal on the pharmacokinetics of a PSMA-targeting ligand for radioligand therapy

Kelly, J., Amor-Coarasa, A., Ponnala, S., Nikolopoulou, A., Williams, C., Babich, J.

Journal:

Nuclear Medicine and Biology

Year:

2019

Language:

english

File:

PDF, 58 KB

english, 2019

25

Effect of the radiometal on the pharmacokinetics of a PSMA-targeting ligand for radioligand therapy

Kelly, J., Amor-Coarasa, A., Ponnala, S., Nikolopoulou, A., Williams, C., Babich, J.

Journal:

Nuclear Medicine and Biology

Year:

2019

File:

PDF, 58 KB

2019

26

3D-printed automation for optimized PET radiochemistry

Amor-Coarasa, Alejandro, Kelly, James M., Babich, John W.

Journal:

Science Advances

Year:

2019

Language:

english

File:

PDF, 9.12 MB

english, 2019

27

Comparison of the IGG-100 vs the ITG 68Ge/68Ga generators: impact of impurities on radiolabeling

Amor-Coarasa, A., Gruka, M., Hurez, S., Gulec, S., Mcgoron, A., Babich, J.

Journal:

Nuclear Medicine and Biology

Year:

2019

Language:

english

File:

PDF, 65 KB

english, 2019

28

Comparison of the IGG-100 vs the ITG 68Ge/68Ga generators: impact of impurities on radiolabeling

Amor-Coarasa, A., Gruka, M., Hurez, S., Gulec, S., Mcgoron, A., Babich, J.

Journal:

Nuclear Medicine and Biology

Year:

2019

File:

PDF, 65 KB

2019

29

Otto: a 4.04âGBq (109âmCi) 68Ge/68Ga generator, first of its kind - extended quality control and performance evaluation in the clinical production of [68Ga]Ga-PSMA-11

Waterhouse, Nicole N., Amor-Coarasa, Alejandro, Nikolopoulou, Anastasia, Babich, John W.

Journal:

EJNMMI Radiopharmacy and Chemistry

Year:

2020

File:

PDF, 665 KB

2020

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